SCHEMBL9683671

SCHEMBL9683671

O=C(NC(=O)c1ccccc1Cl)Nc1cc(Cl)c(Oc2ccc(Cl)cc2)c(Cl)c1

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.75
PNLIP P16233 8/20 0.60
PYGL P06737 4/20 0.58
TDP1 Q9NUW8 1/20 0.57
RAB9A P51151 2/20 0.53
STK39 Q9UEW8 1/20 0.53
NPC1 O15118 1/20 0.53
POLB P06746 1/20 0.53
PKM P14618 1/20 0.53
PLCG2 P16885 1/20 0.47
MAPT P10636 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 2/20 0.46
ALOX12 P18054 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11140710 0.93 GCGR (0.64) GCGRPNLIPPYGLTDP1RAB9A
SCHEMBL9134421 0.91 GCGR (0.62) GCGRPNLIPPYGLTDP1STK39
SCHEMBL8658796 0.90 PNLIP (0.62) GCGRPNLIPPYGLTDP1RAB9A
SCHEMBL8661440 0.88 GCGR (0.59) GCGRPNLIPPYGLTDP1RAB9A
SCHEMBL11138798 0.87 GCGR (0.78) GCGRPNLIPPYGLTDP1RAB9A
SCHEMBL9135999 0.87 GCGR (0.58) GCGRPNLIPPYGLTDP1RAB9A
SCHEMBL8660298 0.83 GCGR (0.54) GCGRPNLIPPYGLTDP1RAB9A
SCHEMBL8658836 0.83 GCGR (0.59) GCGRPNLIPPYGLTDP1RAB9A
SCHEMBL11241471 0.82 PYGL (0.64) GCGRPNLIPPYGLTDP1RAB9A
SCHEMBL8658973 0.82 GCGR (0.58) GCGRPNLIPPYGLTDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166179-A Insecticides LANGE ARNO (DE) 1992-11-24 US disclosed
US-4399152-A Substituted benzoyl ureas as insecticides DUPHAR INTERNATIONAL B.V. (NL) 1983-08-16 US disclosed