SCHEMBL1124153

SCHEMBL1124153

CC(O)C(C(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.56
TSHR P16473 1/20 0.41
SLC7A5 Q01650 1/20 0.38
RNPEP Q9H4A4 1/20 0.33
OR51E2 Q9H255 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10481616 0.84 TP53 (0.47) TP53TSHRSLC7A5
SCHEMBL4721741 0.80 TP53 (0.50) TP53TSHRSLC7A5RNPEP
SCHEMBL5970723 0.80 TP53 (0.50) TP53TSHRSLC7A5RNPEP
SCHEMBL28314569 0.79 TP53 (0.47) TP53TSHRSLC7A5RNPEPCYP1A2
SCHEMBL11124159 0.78 TP53 (0.41) TP53TSHRSLC7A5
Lactic Acid SCHEMBL25194 0.77
Lactic Acid SCHEMBL9716092 0.77
Lactic Acid SCHEMBL22341770 0.77
Lactic Acid SCHEMBL28192680 0.77 TP53 (0.92) TP53TSHRSLC7A5OR51E2
Lactic Acid SCHEMBL27811428 0.77 TP53 (0.92) TP53TSHRSLC7A5OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1871855-B1 DIHYDROXY ENOL COMPOUNDS USED IN CHEMICAL MECHANICAL POLISHING COMPOSITIONS HAVING METAL ION OXIDIZERS DUPONT AIR PROD NANOMATERIALS (US) 2010-03-24 EP claimed
CN-117347441-A Fullerene derivative-based humidity-sensitive material, preparation method thereof and humidity sensor prepared from fullerene derivative-based humidity-sensitive material 中国计量大学 2024-01-05 CN disclosed
US-20180179499-A1 BIOBASED PRODUCTION OF FUNCTIONALIZED ALPHA-SUBSTITUTED ACRYLATES AND C4-DICARBOXYLATES LCY BIOSCIENCES INC. (CA) 2018-06-28 US disclosed
EP-3303375-A1 BIOBASED PRODUCTION OF FUNCTIONALIZED ALPHA-SUBSTITUTED ACRYLATES AND C4-DICARBOXYLATES BioAmber Inc. (US) 2018-04-11 EP disclosed
WO-2016196962-A1 BIOBASED PRODUCTION OF FUNCTIONALIZED ALPHA-SUBSTITUTED ACRYLATES AND C4-DICARBOXYLATES BIOAMBER INC. (US) 2016-12-08 WO disclosed
EP-2581368-A1 CYCLIC CARBODIIMIDE COMPOUND Teijin Limited (JP) 2013-04-17 EP disclosed
US-20130079510-A1 CYCLIC CARBODIIMIDE COMPOUND TEIJIN LIMITED (JP) 2013-03-28 US disclosed
EP-2530111-A1 FILM Teijin Limited (JP) 2012-12-05 EP disclosed
US-20120302676-A1 FILM TEIJIN LIMITED (JP) 2012-11-29 US disclosed
CN-101006393-B Alkali development-type photosensitive resin composition, substrate with protrusions for liquid crystal split orientational control and color filter formed using the same, and liquid crystal display device TOPPAN PRINTING CO.,LTD. (JP) 2011-11-30 CN disclosed
EP-2284167-A2 Crystalline forms of 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide Novartis AG (CH) 2011-02-16 EP disclosed
EP-2284168-A2 Crystalline forms of 4-methyl-n-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide Novartis AG (CH) 2011-02-16 EP disclosed
CN-101006393-A Alkali development-type photosensitive resin composition, substrate with protrusions for liquid crystal split orientational control and color filter formed using the same, and liquid crystal display d TOPPAN PRINTING CO LTD (JP) 2007-07-25 CN disclosed
CN-1876050-A Pharmaceutical preparation for treating prostatitis, its preparation process and quality control method GUIYANG YUNYAN XICHUANG PHARM (CN) 2006-12-13 CN disclosed
CN-1134479-C Process for producing polymer 2004-01-14 CN disclosed
CN-1334834-A Process for producing polymer TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-02-06 CN disclosed
EP-0750230-B1 Negative type photosensitive compositions FUJI PHOTO FILM CO LTD (JP) 1999-02-10 EP disclosed
US-5725994-A CONTAINING AN ACID PRECURSOR AND A HYDROXYL GROUP CONTAINING LINEAR POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1998-03-10 US disclosed
EP-0750230-A2 Negative type photosensitive compositions FUJI PHOTO FILM CO., LTD. (JP) 1996-12-27 EP disclosed
CN-1031280-C Copolymer compositions comprising a copolymer and one or more lubricious additives SHALL INTERNATIONALE RESEARCH (NL) 1996-03-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180179499-A1 BIOBASED PRODUCTION OF FUNCTIONALIZED ALPHA-SUBSTITUTED ACRYLATES AND C4-DICARBOXYLATES COASY, ADSL, ALAD TP53 630/4885TSHR 3786/4885SLC7A5 2822/4885
US-20130079510-A1 CYCLIC CARBODIIMIDE COMPOUND CNOT9, CNOT1, ARPC4 TP53 2628/4885TSHR 2964/4885SLC7A5 3691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.