Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.50 |
| ▸ | CES2 | O00748 | 8/20 | 0.48 |
| ▸ | CES1 | P23141 | 7/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750434 | 0.81 | CES2 (0.65) | CES2CES1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL20362909 | 0.81 | CES1 (0.50) | CES2CES1PRSS1CTSGCTRB1 | |
| SCHEMBL18050312 | 0.80 | ELANE (0.53) | ELANECES2CES1PRSS1CTSG | |
| SCHEMBL18050310 | 0.80 | ELANE (0.53) | ELANECES2CES1PRSS1CTSG | |
| SCHEMBL10796623 | 0.80 | TSHR (0.55) | ELANEPRSS1CTSGCTRB1CMA1 | |
| Methyl Alcohol SCHEMBL9618507 | 0.78 | TSHR (0.53) | ELANEPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL7996356 | 0.78 | CES2 (0.45) | ELANECES2CES1PRSS1CTSG | |
| SCHEMBL27695671 | 0.78 | CES2 (0.58) | ELANECES2CES1ALDH1A1TSHR | |
| SCHEMBL28054392 | 0.78 | CES2 (0.64) | ELANECES2CES1ALDH1A1TSHR | |
| SCHEMBL30368697 | 0.78 | PRSS1 (0.45) | ELANECES1PRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019411-B1 | 1-PHENYL-2-AMINOETHANOL DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-22 | — | — | EP | disclosed |
| US-4338323-A | Piperidylbenzimidazolinone derivatives | SCIENCE UNION ET CIE (FR) | 1982-07-06 | — | — | US | disclosed |