Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248168 | 0.82 | HTR2A (0.47) | IDO1SMN1; SMN2TAAR1CYP2A6HTR2A | |
| SCHEMBL104845 | 0.79 | TDP1 (0.41) | TDP1SMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL139765 | 0.79 | TDP1 (0.35) | TDP1IDO1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8101238 | 0.78 | SMN1; SMN2 (0.40) | TDP1IDO1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4868417 | 0.77 | TDP1 (0.46) | TDP1IDO1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8430157 | 0.75 | POLB (0.39) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL5085393 | 0.75 | TDP1 (0.38) | TDP1SMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL6036848 | 0.75 | IDO1 (0.48) | IDO1SMN1; SMN2L3MBTL1 | |
| SCHEMBL104981 | 0.75 | TDP1 (0.44) | TDP1IDO1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11672508 | 0.74 | TSHR (0.41) | TDP1IDO1ALDH1A1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336395-A | PROCESS FOR PREPARING (AMINOMETHYL) PHENYL-ETHYLDIMETHYLMETHOXYSILANE | PETRARCH SYSTEMS, INC. (US) | 1982-06-22 | — | — | US | claimed |
| US-4336395-A | PROCESS FOR PREPARING (AMINOMETHYL) PHENYL-ETHYLDIMETHYLMETHOXYSILANE | PETRARCH SYSTEMS, INC. (US) | 1982-06-22 | — | — | US | disclosed |