Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 15/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.54 |
| ▸ | WNT3A | P56704 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lotifazole SCHEMBL286772 | 0.90 | ELOVL1 (0.56) | PARP1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11322732 | 0.89 | ABL1 (0.61) | ROCK1ROCK2MEN1ALDH1A1MAPT | |
| SCHEMBL10962623 | 0.88 | ROCK1 (0.50) | ROCK1ROCK2WNT3APARP1MEN1 | |
| SCHEMBL10964259 | 0.85 | MAPT (0.47) | WNT3APARP1ALDH1A1MAPTKMT2A | |
| SCHEMBL10962710 | 0.84 | RAB9A (0.63) | ROCK1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10964529 | 0.84 | RAB9A (0.57) | CLK1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10965815 | 0.83 | RAB9A (0.46) | PARP1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10965935 | 0.82 | HDAC3 (0.57) | ROCK1ROCK2MEN1ALDH1A1MAPT | |
| SCHEMBL10965959 | 0.79 | CFTR (0.49) | ROCK1PARP1MEN1ALDH1A1MAPT | |
| SCHEMBL10962624 | 0.79 | KMT2A (0.63) | MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57118573-A | — | — | None | — | — | JP | disclosed |
| JP-S57118573-A | N-(2-THIAZOLYL)CARBAMATE DERIVATIVE, ITS PREPARATION, AND DRUG COMPOSITION COMPRISING IT | MITSUI TOATSU CHEM INC | 1982-07-23 | — | — | JP | disclosed |