Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CDC25B | P30305 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250173 | 0.88 | CDC25B (0.54) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL10895485 | 0.85 | EGFR (0.57) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8567962 | 0.84 | MEN1 (0.59) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL11244675 | 0.82 | MAPT (0.58) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL11253873 | 0.82 | MAPT (0.57) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL118643 | 0.81 | NAMPT (0.57) | MAPTALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL10895447 | 0.81 | RAB9A (0.54) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL11372606 | 0.78 | KDM4E (0.55) | MAPTALDH1A1CDC25BEGFRKDR | |
| SCHEMBL5068509 | 0.78 | CA1 (0.75) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL122798 | 0.78 | PARP10 (0.67) | MAPTALDH1A1CDC25BL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |