Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567962 | 0.86 | MEN1 (0.59) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL11253873 | 0.84 | MAPT (0.57) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL11241863 | 0.82 | MAPT (0.55) | MAPTRAB9ANPC1SMN1; SMN2GFER | |
| SCHEMBL5068509 | 0.80 | CA1 (0.75) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL11245297 | 0.80 | SMN1; SMN2 (0.68) | MAPTRAB9ANPC1SMN1; SMN2GFER | |
| SCHEMBL30765134 | 0.79 | SMN1; SMN2 (0.62) | MAPTRAB9ANPC1SMN1; SMN2GFER | |
| SCHEMBL11238983 | 0.78 | MAPT (0.71) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL4122902 | 0.77 | TRPV1 (0.65) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL11245753 | 0.77 | MAPT (0.63) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL27996234 | 0.77 | SMN1; SMN2 (0.73) | MAPTRAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |