Pentachlorophenol

Pentachlorophenol

SCHEMBL11241899

C[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 4/20 0.43
CYP2C9 P11712 4/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 3/20 0.42
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 2/20 0.38
MAPK1 P28482 1/20 0.37
CYP2C19 P33261 1/20 0.34
PDE4A P27815 1/20 0.33
USP2 O75604 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sorbitol SCHEMBL2688276 0.89 LMNA (0.55) LMNAL3MBTL1CYP1A2CYP2C9HIF1A
Mannitol SCHEMBL11230894 0.89 LMNA (0.55) LMNAL3MBTL1CYP1A2CYP2C9HIF1A
Pentachlorophenol SCHEMBL11235831 0.85 TSHR (0.50) LMNAL3MBTL1CYP1A2CYP2C9HIF1A
Pentachlorophenol SCHEMBL10591497 0.81 CYP1A2 (0.52) LMNAL3MBTL1CYP1A2CYP2C9HIF1A
Pentachlorophenol SCHEMBL164440 0.80 TSHR (0.56) LMNAL3MBTL1CYP1A2CYP2C9HIF1A
SCHEMBL309466 0.80 LMNA (0.69) LMNAL3MBTL1TDP1TSHRALDH1A1
SCHEMBL2065096 0.80 LMNA (0.69) LMNAL3MBTL1TDP1TSHRALDH1A1
SCHEMBL1017001 0.80 LMNA (0.69) LMNAL3MBTL1TDP1TSHRALDH1A1
SCHEMBL22128527 0.80 LMNA (0.69) LMNAL3MBTL1TDP1TSHRALDH1A1
SCHEMBL13134752 0.80 LMNA (0.69) LMNAL3MBTL1TDP1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4342875-A STABILIZERS FOR OLEFIN POLYMERS CINCINNATI-MILACRON, INC. (US) 1982-08-03 US disclosed