Mannitol

Mannitol

SCHEMBL11230894

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
TDP1 Q9NUW8 1/20 0.52
CYP1A2 P05177 5/20 0.50
CYP2C9 P11712 4/20 0.50
TSHR P16473 3/20 0.50
HIF1A Q16665 3/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP3A4 P08684 1/20 0.41
KDM4E B2RXH2 2/20 0.39
PDE4A P27815 1/20 0.39
MAPK1 P28482 1/20 0.39
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sorbitol SCHEMBL2688276 1.00 LMNA (0.55) LMNAL3MBTL1TDP1CYP1A2CYP2C9
Pentachlorophenol SCHEMBL11235831 0.95 TSHR (0.50) LMNAL3MBTL1TDP1CYP1A2CYP2C9
Pentachlorophenol SCHEMBL164440 0.90 TSHR (0.56) LMNAL3MBTL1TDP1CYP1A2CYP2C9
Pentachlorophenol SCHEMBL11241899 0.89 LMNA (0.44) LMNAL3MBTL1TDP1CYP1A2CYP2C9
Demannose SCHEMBL27278309 0.84 LMNA (0.39) LMNAL3MBTL1TDP1CYP1A2CYP2C9
Demannose SCHEMBL2878983 0.84 LMNA (0.39) LMNAL3MBTL1TDP1CYP1A2CYP2C9
Sorbitol SCHEMBL7107557 0.83 PDE4A (0.41) LMNAL3MBTL1TDP1CYP1A2CYP2C9
Pentachlorophenol SCHEMBL9501530 0.83 CYP1A2 (0.48) LMNAL3MBTL1TDP1CYP1A2CYP2C9
Pentachlorophenol SCHEMBL9362639 0.83 CYP1A2 (0.48) LMNAL3MBTL1TDP1CYP1A2CYP2C9
Pentachlorophenol SCHEMBL18039457 0.83 CYP1A2 (0.48) LMNAL3MBTL1TDP1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117920163-A Method for producing organic sulfur compound JSR株式会社 2024-04-26 CN disclosed
CN-112969532-B Carrier and method for producing the same, and method for detecting or separating chromatographic column and target substance JSR株式会社 2024-02-09 CN disclosed
CN-112969532-A Method for producing organic sulfur compound, carrier, method for producing carrier, ligand-immobilized carrier, chromatography column, and method for detecting or separating target substance JSR株式会社 2021-06-15 CN disclosed
CN-110997133-A Chromatography carrier, ligand-immobilized carrier, chromatography column, method for purifying target substance, and method for producing chromatography carrier JSR株式会社 2020-04-10 CN disclosed
WO-2020045541-A1 CHROMATOGRAPHY CARRIER JSR株式会社 2020-03-05 WO disclosed
US-4342875-A STABILIZERS FOR OLEFIN POLYMERS CINCINNATI-MILACRON, INC. (US) 1982-08-03 US disclosed