Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893081 | 0.84 | KDM4E (0.43) | KDM4ETP53GAANPSR1MEN1 | |
| SCHEMBL7893080 | 0.84 | KDM4E (0.48) | KDM4ETP53GAANPSR1MEN1 | |
| SCHEMBL11423461 | 0.83 | KDM4E (0.33) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7888404 | 0.82 | KDM4E (0.41) | KDM4ETP53GAANPSR1MEN1 | |
| SCHEMBL9160199 | 0.80 | KDM4E (0.40) | KDM4ETP53GAANPSR1MEN1 | |
| SCHEMBL11423008 | 0.77 | MEN1 (0.47) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL7893162 | 0.77 | KDM4E (0.47) | KDM4ETP53GAANPSR1MEN1 | |
| SCHEMBL11421340 | 0.76 | KDM4E (0.33) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL11429827 | 0.76 | KDM4E (0.33) | KDM4EMEN1KMT2ALMNAMAPT | |
| SCHEMBL11424478 | 0.75 | CXCR3 (0.34) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327018-A | Azo dyes and the production and use thereof | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| US-4225491-A | REACTIVE DYES FOR COTTON | ICI UNITED STATES, INC. (US) | 1980-09-30 | — | — | US | disclosed |