Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160199 | 0.82 | KDM4E (0.40) | KDM4ETP53GAANPSR1MEN1 | |
| SCHEMBL11242010 | 0.82 | KDM4E (0.46) | KDM4ETP53GAANPSR1MEN1 | |
| SCHEMBL7891026 | 0.80 | MEN1 (0.42) | KDM4ENPSR1MEN1KMT2ALMNA | |
| SCHEMBL11339850 | 0.80 | KDM4E (0.42) | KDM4ENPSR1MEN1KMT2ALMNA | |
| SCHEMBL11051169 | 0.80 | KDM4E (0.41) | KDM4ENPSR1ALDH1A1HSD17B10MAPT | |
| SCHEMBL11053467 | 0.79 | ALDH1A1 (0.33) | KDM4ENPSR1MEN1KMT2ALMNA | |
| SCHEMBL7893081 | 0.78 | KDM4E (0.43) | KDM4ETP53GAANPSR1MEN1 | |
| SCHEMBL7893080 | 0.78 | KDM4E (0.48) | KDM4ETP53GAANPSR1MEN1 | |
| SCHEMBL11290276 | 0.78 | ALDH1A1 (0.49) | KDM4EGAANPSR1MEN1KMT2A | |
| SCHEMBL6875333 | 0.77 | KDM4E (0.40) | KDM4ENPSR1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177552-B1 | CONTAINING (((VINYLSULFONYL)ALKYLAMINO)ALKYLSULFONYL)PHENYLAZO GROUPS | DYSTARTEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2001-01-23 | — | — | US | disclosed |
| EP-0489360-B1 | Water-soluble azocompounds, process for their preparation and their use as dyes | HOECHST AG (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0399411-B1 | Water soluble azo compounds, process for their preparation and their use as dyestuffs | HOECHST AG (DE) | 1994-07-13 | — | — | EP | disclosed |
| EP-0381133-B1 | Water soluble azo compounds, method for their preparation and their use as dyestuffs | HOECHST AG (DE) | 1994-03-02 | — | — | EP | disclosed |
| EP-0384276-B1 | Water soluble azo compounds, method for their preparation and their use as dyestuffs | HOECHST AG (DE) | 1993-11-10 | — | — | EP | disclosed |
| US-5216138-A | With vinyl sulfonyl group | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0489360-A1 | Water-soluble azocompounds, process for their preparation and their use as dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-10 | — | — | EP | disclosed |
| US-5021559-A | Water-soluble azo compounds containing a fiber-reactive group of the vinylsulfone series, suitable as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| US-5010180-A | Printing, dyeing | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| EP-0399411-A1 | Water soluble azo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-11-28 | — | — | EP | disclosed |
| EP-0381133-A1 | Water soluble azo compounds, method for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-08 | — | — | EP | disclosed |
| EP-0078024-B1 | WATER-SOLUBLE PYRIDONE AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-19 | — | — | EP | disclosed |