Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242557 | 1.00 | ALDH1A1 (0.45) | ALDH1A1GAAKMT2AMEN1ESR1 | |
| SCHEMBL2833082 | 0.86 | LMNA (0.51) | ALDH1A1GAAKMT2AMEN1ESR1 | |
| SCHEMBL11102517 | 0.84 | CA1 (0.42) | ALDH1A1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL11102510 | 0.84 | CA1 (0.42) | ALDH1A1LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL11108989 | 0.83 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPK1PRSS1ACR | |
| SCHEMBL11110206 | 0.82 | CYP2C19 (0.48) | ALDH1A1GAAKMT2AMEN1ESR1 | |
| SCHEMBL15249772 | 0.79 | MEN1 (0.50) | ALDH1A1GAAKMT2AMEN1ESR1 | |
| SCHEMBL3721273 | 0.77 | MAPT (0.49) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL2834181 | 0.77 | MAPT (0.49) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL21939149 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317920-A | ANTIRHEUMATIC AGENTS, ANTIINFLAMMATORY AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1982-03-02 | — | — | US | claimed |