Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 11/20 | 0.97 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044600 | 1.00 | HCAR3 (0.97) | HCAR3PRSS1MAPTGAANPC1 | |
| SCHEMBL11208444 | 1.00 | HCAR3 (0.97) | HCAR3PRSS1MAPTGAANPC1 | |
| SCHEMBL6044024 | 0.99 | HCAR3 (1.00) | HCAR3PRSS1MAPTGAANPC1 | |
| SCHEMBL6044176 | 0.95 | HCAR3 (1.00) | HCAR3PRSS1MAPTGAANPC1 | |
| SCHEMBL2688335 | 0.89 | HCAR3 (1.00) | HCAR3MAPTNPC1ALDH1A1PKM | |
| SCHEMBL9192588 | 0.86 | HCAR3 (0.77) | HCAR3PRSS1MAPTNPC1ALDH1A1 | |
| SCHEMBL15321333 | 0.85 | MAPT (0.82) | HCAR3PRSS1MAPTNPC1ALDH1A1 | |
| SCHEMBL10524428 | 0.85 | HCAR3 (0.76) | HCAR3PRSS1MAPTGAANPC1 | |
| SCHEMBL3278681 | 0.85 | HCAR3 (0.78) | HCAR3PRSS1MAPTALDH1A1 | |
| SCHEMBL9247817 | 0.85 | HCAR3 (0.71) | HCAR3PRSS1MAPTGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347180-A | High caustic coupling process for preparing substituted 2-nitro-2'-hydroxyazobenzenes | CIBA-GEIGY CORPORATION (US) | 1982-08-31 | — | — | US | disclosed |
| US-4275004-A | High caustic coupling process for preparing substituted 2-nitro-2'-hydroxyazobenzenes | CIBA-GEIGY CORPORATION (US) | 1981-06-23 | — | — | US | disclosed |
| US-4230867-A | REDUCTION, CYCLIZATION OF NITROAZOBENZENES | CIBA-GEIGY CORPORATION (US) | 1980-10-28 | — | — | US | disclosed |
| US-4219480-A | REDUCTION OF UNDESIRED BY-PRODUCT AND EFFLUENT POLLUTION PROBLEMS | CIBA-GEIGY CORPORATION (US) | 1980-08-26 | — | — | US | disclosed |
| US-4141903-A | REDUCTION AND CYCLIZATION OF THE CORRESPONDING O-NITROAZOBENZENES WITH CARBON MONOXIDE USING A COPPER-AMINE COMPLEX AS CATALYST | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |
| US-4041044-A | BY REDUCTION OF CORRESPONDING O-NITRO-AZOBENZENES WITH ZINC IN AQUEOUS ALKALI METAL HYDROXIDE | CIBA-GEIGY CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |