Benzene

Benzene

SCHEMBL11242974

COc1ccc(C)cc1.c1ccccc1

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.88
RELA Q04206 1/20 0.65
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA12 O43570 1/20 0.65
CA14 Q9ULX7 1/20 0.65
CA4 P22748 1/20 0.63
LTA4H P09960 2/20 0.59
NPC1 O15118 4/20 0.54
RAB9A P51151 4/20 0.54
KMT2A Q03164 1/20 0.54
TRPA1 O75762 1/20 0.52
MAPK1 P28482 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPT P10636 2/20 0.48
GAA P10253 2/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL5205324 0.95 ACHE (0.79) ACHERELACA1CA2CA7
SCHEMBL12464 0.94
SCHEMBL19182839 0.94 ACHE (1.00) ACHERELACA1CA2CA7
SCHEMBL13925529 0.94
SCHEMBL7076971 0.91 ACHE (0.94) ACHERELACA1CA2CA7
Methoxymethane SCHEMBL20136157 0.91 ACHE (0.94) ACHERELACA1CA2CA7
SCHEMBL28860327 0.91 ACHE (0.94) ACHERELACA1CA2CA7
Ammonia Solution, Strong SCHEMBL21437378 0.91 ACHE (0.94) ACHERELACA1CA2CA7
SCHEMBL29169384 0.91 ACHE (0.94) ACHERELACA1CA2CA7
Methyl Alcohol SCHEMBL20136156 0.88 ACHE (0.88) ACHERELACA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4318783-A Process for the preparation of optionally substituted benzaldehyde dialkyl acetals BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed