Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.67 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.67 |
| ▸ | CHRNG | P07510 | 4/20 | 0.67 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.67 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.67 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.67 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.67 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.67 |
| ▸ | CHRND | Q07001 | 4/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770039 | 0.83 | SLC6A3 (0.78) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL770607 | 0.80 | SLC6A3 (1.00) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL69263 | 0.77 | KDM4E (0.62) | CYP2C19ALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL2890548 | 0.76 | KDM4E (0.51) | CYP2C19ALDH1A1SMN1; SMN2KDM4ES1PR1 | |
| SCHEMBL5781341 | 0.76 | KDM4E (0.49) | CYP2C19ALDH1A1SMN1; SMN2KDM4ES1PR1 | |
| Hydrochloric Acid SCHEMBL11115701 | 0.75 | SLC6A3 (0.58) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL6243384 | 0.75 | KDM4E (0.50) | CYP2C19ALDH1A1SMN1; SMN2KDM4ES1PR1 | |
| SCHEMBL1483403 | 0.75 | TSHR (0.55) | ALDH1A1SMN1; SMN2KDM4ES1PR1S1PR3 | |
| SCHEMBL770391 | 0.75 | SLC6A3 (0.67) | SLC6A3SLC6A2CHRNA1CHRNGCHRNB1 | |
| SCHEMBL29606273 | 0.75 | TSHR (0.55) | ALDH1A1SMN1; SMN2KDM4ES1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356165-A | Bupropion radioimmunoassay, and kit | BURROUGHS WELLCOME CO. (US) | 1982-10-26 | — | — | US | claimed |
| US-4356165-A | Bupropion radioimmunoassay, and kit | BURROUGHS WELLCOME CO. (US) | 1982-10-26 | — | — | US | disclosed |
| US-4355179-A | Radioactive nuclide labeled propiophenone compounds | BURROUGHS WELLCOME CO. (US) | 1982-10-19 | — | — | US | disclosed |
| US-4347177-A | Compounds and methods of making them | BURROUGHS WELLCOME CO. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4347382-A | 3H Labeled compounds | BURROUGHS WELLCOME CO. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4347176-A | Compounds and methods of making same | BURROUGHS WELLCOME CO. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4347178-A | Compounds and methods of making | BURROUGHS WELLCOME CO. (US) | 1982-08-31 | — | — | US | disclosed |
| EP-0038071-A2 | New unlabelled and radioactive labelled derivatives of butylamino propiophenone, their preparation, immunogens obtained from the unlabelled derivatives and a process for immunogen preparation, antisera raised using the immunogens and a method for raising antisera, a radioimmunoassay method and a test kit for use in the assay method | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-10-21 | — | — | EP | disclosed |