Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 4/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243257 | 0.83 | APP (0.42) | BACE1APPKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL14675605 | 0.75 | ALOX5 (0.55) | PELI1ALOX5BACE1ESR2GRIN2D | |
| SCHEMBL14675604 | 0.75 | ALOX5 (0.55) | PELI1ALOX5BACE1ESR2GRIN2D | |
| SCHEMBL8076350 | 0.72 | KMT2A (0.52) | APPKDM4EALDH1A1L3MBTL1GRIN2D | |
| SCHEMBL9635204 | 0.72 | KMT2A (0.52) | APPKDM4EALDH1A1L3MBTL1GRIN2D | |
| SCHEMBL8076349 | 0.72 | KMT2A (0.52) | APPKDM4EALDH1A1L3MBTL1GRIN2D | |
| SCHEMBL2160707 | 0.69 | GRIN2D (0.59) | BACE1ALDH1A1L3MBTL1GRIN2DGRIN3B | |
| SCHEMBL3323469 | 0.69 | GRIN2D (0.59) | BACE1ALDH1A1L3MBTL1GRIN2DGRIN3B | |
| SCHEMBL2160705 | 0.69 | GRIN2D (0.59) | BACE1ALDH1A1L3MBTL1GRIN2DGRIN3B | |
| SCHEMBL4686720 | 0.68 | KMT2A (0.54) | KDM4EALDH1A1L3MBTL1KMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352896-A | Polyol mixtures containing reactive blowing agents and use thereof for the production of foamed polyurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-10-05 | — | — | US | disclosed |