Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243249 | 0.92 | LMNA (0.45) | LMNAALDH1A1ALDH2MMP1MMP2 | |
| SCHEMBL1628754 | 0.91 | LMNA (0.43) | LMNAALDH1A1ALDH2CA12CA1 | |
| SCHEMBL1042979 | 0.87 | LMNA (0.40) | LMNAALDH1A1ALDH2MMP1MMP2 | |
| SCHEMBL648954 | 0.87 | CES2 (0.46) | ALDH1A1KMT2AALOX15TSHRPDE4A | |
| SCHEMBL194525 | 0.87 | CES2 (0.46) | ALDH1A1KMT2AALOX15TSHRPDE4A | |
| SCHEMBL1629859 | 0.86 | LMNA (0.41) | LMNAALDH1A1ALDH2MMP1MMP2 | |
| SCHEMBL2505688 | 0.86 | BLM (0.43) | LMNAALDH1A1ALDH2KMT2ACYP1A2 | |
| SCHEMBL2503822 | 0.82 | LMNA (0.38) | LMNAALDH1A1ALDH2MMP1MMP2 | |
| SCHEMBL11523442 | 0.80 | LMNA (0.39) | LMNAALDH1A1ALDH2MMP1MMP2 | |
| SCHEMBL19359715 | 0.78 | LMNA (0.37) | LMNAALDH1A1ALDH2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322491-A | BINDER, PHOTOINITIATOR, AND AN UNSATURATED COMPOUND | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |