Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MPL | P40238 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302691 | 0.87 | CYP2D6 (0.49) | TRPM4CYP2D6CA2CA1CA9 | |
| SCHEMBL154163 | 0.84 | CA2 (0.52) | TRPM4CYP2D6CA2CA1CA9 | |
| SCHEMBL29459215 | 0.84 | CA2 (0.52) | TRPM4CYP2D6CA2CA1CA9 | |
| SCHEMBL31450788 | 0.81 | CYP2D6 (0.58) | TRPM4CYP2D6NQO2MPLCYP2C9 | |
| SCHEMBL11575592 | 0.81 | CA1 (0.55) | TRPM4CYP2D6CA2CA1CA9 | |
| SCHEMBL564215 | 0.81 | CYP2D6 (0.58) | TRPM4CYP2D6NQO2MPLCYP2C9 | |
| SCHEMBL3035364 | 0.78 | ERN1 (0.53) | CA2CA1CA9LDHAPKM | |
| SCHEMBL1126146 | 0.77 | CYP2D6 (0.54) | TRPM4CYP2D6CA2CA1CA9 | |
| SCHEMBL10383546 | 0.77 | CYP2D6 (0.43) | TRPM4CYP2D6CA2CA1CA9 | |
| SCHEMBL3262066 | 0.76 | CYP2D6 (0.66) | TRPM4CYP2D6NQO2PKMMPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335254-A | Polymerizable acryloyloxyarylenesulfonamides | EASTMAN KODAK COMPANY (US) | 1982-06-15 | — | — | US | disclosed |
| US-4289865-A | USEFUL IN RELIEF IMAGES OR AS BINDERS IN PHOTOGRAPHIC MATERIALS | EASTMAN KODAK COMPANY (US) | 1981-09-15 | — | — | US | disclosed |