Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.55 |
| ▸ | CA2 | P00918 | 7/20 | 0.55 |
| ▸ | CA9 | Q16790 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154163 | 0.84 | CA2 (0.52) | CA1CA2CA9CA12LDHA | |
| SCHEMBL29459215 | 0.84 | CA2 (0.52) | CA1CA2CA9CA12LDHA | |
| SCHEMBL11243318 | 0.81 | TRPM4 (0.50) | CA1CA2CA9CA12LDHA | |
| SCHEMBL3149871 | 0.80 | CA1 (0.59) | CA1CA2CA9CA12LDHA | |
| SCHEMBL3922877 | 0.78 | CA1 (0.62) | CA1CA2CA9CA12LDHA | |
| SCHEMBL15428777 | 0.77 | CA2 (0.58) | CA1CA2CA9CA12LDHA | |
| SCHEMBL11302691 | 0.76 | CYP2D6 (0.49) | CA1CA2CA9LDHALMNA | |
| SCHEMBL8415193 | 0.74 | CA2 (0.43) | CA1CA2CA9CA12LMNA | |
| SCHEMBL1807638 | 0.73 | CA2 (0.60) | CA1CA2CA9CA12LDHA | |
| SCHEMBL4559508 | 0.73 | CA1 (0.60) | CA1CA2CA9CA12LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172089-A | COMPLEMENT INHIBITOR TRI- OR HEXA-PHENYL ESTER INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| US-4117003-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-09-26 | — | — | US | disclosed |