⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10385468 | 0.80 | KDM4E (0.39) | — | |
| SCHEMBL11395090 | 0.73 | EPHX1 (0.36) | — | |
| SCHEMBL25055377 | 0.71 | — | — | |
| SCHEMBL11028926 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL124179 | 0.69 | — | — | |
| SCHEMBL6363154 | 0.69 | — | — | |
| SCHEMBL6722099 | 0.69 | — | — | |
| SCHEMBL21440375 | 0.69 | — | — | |
| SCHEMBL22947147 | 0.69 | — | — | |
| Chloromethane SCHEMBL10874359 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524937-B2 | Indirubin derivatives, and uses thereof | CITY OF HOPE (US) | 2022-12-13 | — | — | US | disclosed |
| US-20200247750-A1 | INDIRUBIN DERIVATIVES, AND USES THEREOF | CITY OF HOPE | 2020-08-06 | — | — | US | disclosed |
| US-10435367-B2 | Indirubin derivatives, and uses thereof | CITY OF HOPE (US) | 2019-10-08 | — | — | US | disclosed |
| US-4323704-A | ENZYME INHIBITORS USEFUL AGAINST BACTERIA, FUNGUS AND VIRAL INFECTIONS, MALE ANTIFERTILITY AGENTS, IMMUNO-SUPPRESSANTS, AND ANTITUMOR ACTIVITY | MERRELL TORAUDE ET COMPAGNIE (FR) | 1982-04-06 | — | — | US | disclosed |
| US-4267374-A | BACTERICIDES; VIRICIDES; FUNGICIDES; INHIBITORS OF HYDROLASE ENZYMES; INTERMEDIATE FOR CEPHALOSPORIN COMPOUND | MERRELL TORAUDE ET COMPAGNIE (FR) | 1981-05-12 | — | — | US | disclosed |
| US-4088667-A | ANTIBACTERIAL AGENTS, PHARMACOLOGICAL INTERMEDIATES | MERRELL TORAUDE ET COMPAGNIE (FR) | 1978-05-09 | — | — | US | disclosed |