Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 15/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 15/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRND | Q07001 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351738 | 0.88 | OPRM1 (0.67) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11252499 | 0.83 | OPRL1 (0.49) | OPRL1OPRM1OPRK1SLC6A2SLC6A3 | |
| SCHEMBL8352749 | 0.79 | OPRL1 (0.58) | OPRL1OPRM1OPRK1 | |
| SCHEMBL8353443 | 0.79 | OPRL1 (0.58) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11245467 | 0.79 | OPRM1 (0.58) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL3407450 | 0.76 | OPRL1 (0.54) | OPRL1OPRM1OPRK1 | |
| SCHEMBL27826334 | 0.75 | OPRM1 (0.50) | OPRL1OPRM1OPRK1 | |
| SCHEMBL25160799 | 0.73 | OPRM1 (0.66) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11078629 | 0.73 | OPRL1 (0.51) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3407452 | 0.73 | OPRL1 (0.51) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366172-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1982-12-28 | — | — | US | disclosed |