Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407450 | 0.84 | OPRL1 (0.54) | OPRL1OPRM1OPRK1MAOBMAOA | |
| SCHEMBL8351738 | 0.83 | OPRM1 (0.67) | OPRL1OPRM1OPRK1MAOBMAOA | |
| SCHEMBL517788 | 0.83 | OPRM1 (0.44) | OPRL1OPRM1OPRK1MEN1CYP2C9 | |
| SCHEMBL4014546 | 0.83 | OPRM1 (0.46) | OPRL1OPRM1OPRK1MEN1CYP2C9 | |
| SCHEMBL4022665 | 0.83 | OPRM1 (0.44) | OPRL1OPRM1OPRK1MEN1CYP2C9 | |
| SCHEMBL517752 | 0.82 | OPRL1 (0.69) | OPRL1OPRM1OPRK1MEN1CYP2C9 | |
| Hydrochloric Acid SCHEMBL11098093 | 0.81 | OPRM1 (0.42) | OPRL1OPRM1OPRK1MEN1CYP2C9 | |
| SCHEMBL3404808 | 0.80 | OPRM1 (0.65) | OPRL1OPRM1OPRK1MAOBMAOA | |
| Ethylene SCHEMBL11079292 | 0.80 | OPRM1 (0.41) | OPRL1OPRM1OPRK1MEN1CYP2C9 | |
| SCHEMBL11099050 | 0.80 | OPRM1 (0.46) | OPRL1OPRM1OPRK1MEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | claimed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | claimed |
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4366172-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4059448-A | SILVER HALIDE, POLY(2-DIETHYLAMINOETHYL METHACRYLATE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-11-22 | — | — | US | disclosed |