Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243572 | 1.00 | GRIK1 (0.42) | GRIK1GRIK2ALDH1A1TDP1CES1 | |
| SCHEMBL5423161 | 0.83 | GRIK1 (0.41) | GRIK1GRIK2ALDH1A1CES1EP300 | |
| SCHEMBL9017205 | 0.81 | GRIK1 (0.40) | GRIK1GRIK2ALDH1A1CES1 | |
| SCHEMBL9017202 | 0.81 | GRIK1 (0.40) | GRIK1GRIK2ALDH1A1CES1 | |
| SCHEMBL28241897 | 0.80 | GRIK1 (0.42) | GRIK1GRIK2ALDH1A1TDP1CES1 | |
| SCHEMBL3656820 | 0.80 | GRIK1 (0.57) | GRIK1GRIK2ALDH1A1BACE1EP300 | |
| SCHEMBL714325 | 0.80 | GRIK1 (0.57) | GRIK1GRIK2ALDH1A1BACE1EP300 | |
| SCHEMBL714326 | 0.80 | GRIK1 (0.57) | GRIK1GRIK2ALDH1A1BACE1EP300 | |
| SCHEMBL11039754 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL11039756 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315032-A | ANTITHROMBOGENIC AGENTS, ANTIULCER AGENTS | TEITIN LIMITED (JP) | 1982-02-09 | — | — | US | disclosed |
| EP-0019475-A2 | Process for preparing adjacently disubstituted ketones, novel prostaglandins E1 and anti-thrombotic compositions containing them | TEIJIN LIMITED (JP) | 1980-11-26 | — | — | EP | disclosed |