Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243567 | 0.83 | GRIK1 (0.42) | GRIK1GRIK2CES1FFAR3ALDH1A1 | |
| SCHEMBL11243572 | 0.83 | GRIK1 (0.42) | GRIK1GRIK2CES1FFAR3ALDH1A1 | |
| SCHEMBL11243321 | 0.83 | CES1 (0.39) | GRIK1GRIK2CES1CES2HDAC3 | |
| SCHEMBL11243324 | 0.83 | CES1 (0.39) | GRIK1GRIK2CES1CES2HDAC3 | |
| SCHEMBL11038523 | 0.83 | TSHR (0.37) | GRIK1GRIK2CES1CES2HDAC3 | |
| SCHEMBL11043119 | 0.83 | TSHR (0.32) | GRIK1GRIK2CES1CES2HDAC3 | |
| SCHEMBL11043117 | 0.83 | TSHR (0.32) | GRIK1GRIK2CES1CES2HDAC3 | |
| SCHEMBL11038524 | 0.83 | TSHR (0.37) | GRIK1GRIK2CES1CES2HDAC3 | |
| SCHEMBL811730 | 0.81 | GRIK1 (0.55) | GRIK1GRIK2CES1CES2HDAC3 | |
| SCHEMBL4246377 | 0.81 | GRIK1 (0.55) | GRIK1GRIK2CES1CES2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112220-A1 | Hydroformylation of butenes comprising isobutylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-05-17 | — | — | US | claimed |
| EP-0024088-A1 | PROCESS FOR THE PREPARATION OF ALDEHYDES | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1981-02-25 | — | — | EP | disclosed |
| WO-1980001691-A1 | PROCESS FOR THE PREPARATION OF ALDEHYDES | EXXON RESEARCH ENGINEERING CO (US) | 1980-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112220-A1 | Hydroformylation of butenes comprising isobutylene | HMOX2, BBOX1, HMOX1 | GRIK1 3844/4885GRIK2 2605/4885CES1 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.