Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 1/20 | 0.32 |
| ▸ | ATP4B | P51164 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30929883 | 0.70 | CYP4F2 (0.34) | ATP4AATP4BMAPTL3MBTL1LTA4H | |
| SCHEMBL6281711 | 0.66 | CNR2 (0.35) | SMN1; SMN2 | |
| SCHEMBL638679 | 0.63 | MAOA (0.35) | MAOAMAOBHTT | |
| SCHEMBL23070558 | 0.57 | HTT (0.40) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL23181355 | 0.56 | MAOB (0.56) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL19684473 | 0.55 | MAOB (0.40) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL11324668 | 0.54 | LMNA (0.52) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL11009131 | 0.53 | TSHR (0.52) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL6469379 | 0.53 | TSHR (0.52) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL339813 | 0.52 | LMNA (0.82) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358454-A | ANTIULCER AGENT | SCHERING CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |