Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252100 | 1.00 | LDHA (0.79) | LDHALMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL11249901 | 0.94 | LDHA (0.83) | LDHALMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL11246544 | 0.88 | LDHA (1.00) | LDHALMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL11259412 | 0.87 | LMNA (0.66) | LDHALMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL11247021 | 0.87 | SMN1; SMN2 (0.66) | LDHALMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL11254560 | 0.87 | SMN1; SMN2 (0.66) | LDHALMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL11264671 | 0.87 | SMN1; SMN2 (0.66) | LDHALMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL11255342 | 0.87 | LMNA (0.66) | LDHALMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL11258102 | 0.87 | SMN1; SMN2 (0.66) | LDHALMNASMN1; SMN2S1PR2NPSR1 | |
| SCHEMBL11254757 | 0.87 | SMN1; SMN2 (0.66) | LDHALMNASMN1; SMN2S1PR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |