Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240899 | 0.85 | ALDH1A1 (0.38) | ALDH1A1TDP1HTTSMN1; SMN2 | |
| SCHEMBL11236134 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TDP1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11253207 | 0.80 | RGS12 (0.30) | — | |
| SCHEMBL11254230 | 0.77 | HSD17B10 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL11253951 | 0.77 | HSD17B10 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL11233995 | 0.77 | LMNA (0.35) | ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL11257874 | 0.74 | MEN1 (0.36) | ALDH1A1TDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11250294 | 0.74 | HSD17B10 (0.40) | ALDH1A1TDP1HTTSMN1; SMN2 | |
| SCHEMBL11230814 | 0.74 | HSD17B10 (0.40) | ALDH1A1TDP1HTTSMN1; SMN2 | |
| SCHEMBL11243223 | 0.74 | HSD17B10 (0.40) | ALDH1A1TDP1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | disclosed |