Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235538 | 0.88 | HTT (0.47) | TSHRHSD17B10HTTLMNACYP2D6 | |
| SCHEMBL11244731 | 0.87 | TSHR (0.43) | TSHRHSD17B10MAPTHTTLMNA | |
| Hydrochloric Acid SCHEMBL11239639 | 0.87 | HTT (0.46) | TSHRHSD17B10HTTLMNACYP2D6 | |
| Hydrochloric Acid SCHEMBL11237741 | 0.86 | TSHR (0.43) | TSHRHSD17B10MAPTHTTLMNA | |
| SCHEMBL11231201 | 0.85 | NPC1 (0.43) | MAPTHTTLMNACYP2D6ADRB2 | |
| SCHEMBL11229502 | 0.84 | THRB (0.46) | MAPTHTTLMNACYP2D6ADRB2 | |
| Hydrochloric Acid SCHEMBL11226919 | 0.84 | ADRB2 (0.42) | MAPTHTTLMNACYP2D6ADRB2 | |
| Hydrochloric Acid SCHEMBL11238434 | 0.83 | THRB (0.46) | MAPTHTTLMNACYP2D6ADRB2 | |
| Hydrochloric Acid SCHEMBL11230529 | 0.81 | MAPT (0.50) | MAPTHTTLMNACYP2D6ADRB2 | |
| SCHEMBL11241653 | 0.81 | NPC1 (0.38) | TSHRHSD17B10MAPTLMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |