Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250541 | 0.90 | HMOX1 (0.48) | IDO1CYP19A1CYP11B1CYP11B2FNTA | |
| SCHEMBL11232771 | 0.90 | IDO1 (0.41) | IDO1CYP19A1CYP11B1CYP11B2FNTA | |
| SCHEMBL11243302 | 0.90 | ALDH1A1 (0.41) | IDO1CYP19A1CYP11B1CYP11B2FNTA | |
| SCHEMBL11237866 | 0.90 | HMOX1 (0.49) | HMOX1 | |
| SCHEMBL11239983 | 0.88 | HMOX1 (0.44) | IDO1CYP19A1CYP11B1CYP11B2FNTA | |
| SCHEMBL11246053 | 0.88 | IDO1 (0.40) | IDO1CYP19A1CYP11B1CYP11B2FNTA | |
| SCHEMBL11234779 | 0.87 | CYP19A1 (0.46) | CYP19A1CYP11B1HMOX1 | |
| SCHEMBL11242420 | 0.86 | CYP11B1 (0.54) | CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11237614 | 0.84 | CYP1A2 (0.47) | CYP19A1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11237568 | 0.82 | HMOX1 (0.56) | IDO1HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |