Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780821 | 0.95 | CHRM2 (0.57) | CHRM2KCNH2TSHRMAPTHDAC3 | |
| SCHEMBL11238993 | 0.89 | KCNH2 (0.63) | CHRM2KCNH2TSHRHDAC3HDAC1 | |
| SCHEMBL8780928 | 0.88 | KCNH2 (0.60) | CHRM2KCNH2TSHRMAPTKCNJ1 | |
| SCHEMBL11236700 | 0.88 | KCNH2 (0.66) | CHRM2KCNH2HDAC3HDAC1HDAC2 | |
| SCHEMBL11233919 | 0.88 | KCNH2 (0.66) | CHRM2KCNH2HDAC3HDAC1HDAC2 | |
| SCHEMBL11235448 | 0.88 | KCNH2 (0.66) | CHRM2KCNH2HDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL11229997 | 0.88 | KCNH2 (0.62) | CHRM2KCNH2TSHRHDAC3HDAC1 | |
| Bromide SCHEMBL10353478 | 0.87 | KCNH2 (0.59) | CHRM2KCNH2TSHRMAPTKCNJ1 | |
| Hydrochloric Acid SCHEMBL11236309 | 0.86 | KCNH2 (0.64) | CHRM2KCNH2HDAC3HDAC1HDAC2 | |
| Dimethylamine SCHEMBL8780943 | 0.85 | KCNH2 (0.57) | CHRM2KCNH2TSHRMAPTKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336269-A | ANTIARRHYTHMIA | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4277501-A | ANTIARRHYTHMIA AGENTS | ELI LILLY AND COMPANY (US) | 1981-07-07 | — | — | US | disclosed |