SCHEMBL11243845

SCHEMBL11243845

Cc1ccccc1C(=O)NC(=O)Nc1cc(C)c(OCc2ccccc2)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP5 Q96HI0 1/20 0.50
SENP2 Q9HC62 1/20 0.50
SENP1 Q9P0U3 1/20 0.50
GAA P10253 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HPGD P15428 2/20 0.46
SGMS2 Q8NHU3 1/20 0.45
ALDH1A1 P00352 3/20 0.44
POLB P06746 2/20 0.44
ALOX12 P18054 1/20 0.44
PYGL P06737 1/20 0.44
RECQL P46063 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
FFAR1 O14842 1/20 0.44
KIT P10721 2/20 0.44
PDGFRA P16234 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.43
SIRT2 Q8IXJ6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11230531 0.91 MAPT (0.47) SENP5SENP2SENP1ALDH1A1POLB
SCHEMBL8662510 0.90 PYGL (0.57) SENP5SENP2SENP1SMN1; SMN2ALDH1A1
SCHEMBL11393574 0.87 FFAR1 (0.51) SENP5SENP2SENP1GAASMN1; SMN2
SCHEMBL11230042 0.86 MEN1 (0.50) SENP5SENP2SENP1GAASGMS2
SCHEMBL11240053 0.83 PYGL (0.53) SENP5SENP2SENP1ALDH1A1POLB
SCHEMBL11233954 0.83 NPC1 (0.46) SENP5SENP2SENP1GAASMN1; SMN2
SCHEMBL11388299 0.81 FFAR1 (0.56) GAASMN1; SMN2HPGDSGMS2ALDH1A1
SCHEMBL11386722 0.80 RXRA (0.53) GAASMN1; SMN2HPGDSGMS2ALDH1A1
SCHEMBL11243077 0.79 PYGL (0.69) SENP5SENP2SENP1SMN1; SMN2SGMS2
SCHEMBL11247452 0.79 S1PR1 (0.63) GAASMN1; SMN2HPGDSGMS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4350706-A MITICIDES, LARVICIDES DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1982-09-21 US disclosed