Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250634 | 0.99 | P2RX7 (0.47) | P2RX7KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11249329 | 0.83 | P2RX7 (0.49) | P2RX7KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6070905 | 0.78 | PDE4D (0.47) | ALDH1A1HPGDPDE7AKMT2ATSHR | |
| SCHEMBL21462804 | 0.75 | P2RX7 (0.44) | P2RX7 | |
| SCHEMBL3322964 | 0.73 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL3002913 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HSD17B10L3MBTL1NPSR1KMT2A | |
| SCHEMBL20551562 | 0.70 | MAPK1 (0.47) | KDM4EALDH1A1HPGDHSD17B10PDE7A | |
| SCHEMBL11243221 | 0.70 | KDM4E (0.49) | P2RX7KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL880710 | 0.69 | NPSR1 (0.41) | KDM4EALDH1A1HPGDHSD17B10PDE7A | |
| SCHEMBL4751212 | 0.69 | HPGD (0.42) | P2RX7KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |