Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | MMP9 | P14780 | 3/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248743 | 0.95 | HSD17B10 (0.37) | LMNAMEN1KMT2AHSD17B10MMP2 | |
| SCHEMBL11257874 | 0.90 | MEN1 (0.36) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11233995 | 0.87 | LMNA (0.35) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11236916 | 0.85 | HSD17B10 (0.41) | LMNATP53ALDH1A1MEN1KMT2A | |
| SCHEMBL11230814 | 0.84 | HSD17B10 (0.40) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11243223 | 0.84 | HSD17B10 (0.40) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11238643 | 0.84 | HSD17B10 (0.40) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11250294 | 0.84 | HSD17B10 (0.40) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11382693 | 0.84 | TSHR (0.38) | LMNAALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11253951 | 0.82 | HSD17B10 (0.40) | LMNATP53ALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | claimed |
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | disclosed |