Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243223 | 1.00 | HSD17B10 (0.40) | HSD17B10ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL11250294 | 1.00 | HSD17B10 (0.40) | HSD17B10ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL11230814 | 1.00 | HSD17B10 (0.40) | HSD17B10ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL11236916 | 0.94 | HSD17B10 (0.41) | HSD17B10ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11253951 | 0.93 | HSD17B10 (0.40) | HSD17B10ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL11254230 | 0.93 | HSD17B10 (0.40) | HSD17B10ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL11236134 | 0.90 | ALDH1A1 (0.43) | HSD17B10ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL11257874 | 0.88 | MEN1 (0.36) | HSD17B10ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL11243898 | 0.84 | LMNA (0.35) | HSD17B10ALDH1A1TDP1LMNAMEN1 | |
| SCHEMBL11240537 | 0.81 | HSD17B10 (0.39) | HSD17B10ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | claimed |
| US-4329460-A | ANTICANCER AGENTS, ANTIVIRAL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-05-11 | — | — | US | disclosed |