Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253473 | 0.74 | ACHE (0.53) | SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL1833770 | 0.68 | POLB (0.62) | SMN1; SMN2LMNAMAPTALDH1A1POLB | |
| SCHEMBL11363099 | 0.66 | ACHE (0.54) | SMN1; SMN2LMNAMAPTALDH1A1NPSR1 | |
| SCHEMBL2873979 | 0.65 | CHKA (0.72) | SMN1; SMN2MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL6171317 | 0.65 | MAPT (0.57) | SMN1; SMN2MAPTALDH1A1POLBHPGD | |
| SCHEMBL10837355 | 0.65 | KDM4E (0.69) | ALDH1A1 | |
| SCHEMBL5561237 | 0.65 | POLB (0.74) | LMNAMAPTALDH1A1POLBHPGD | |
| SCHEMBL228900 | 0.64 | CHKA (0.71) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL1335735 | 0.64 | CHKA (0.71) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3882134 | 0.64 | CHKA (0.71) | SMN1; SMN2MAPTALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318858-A | ANTIHISTAMINES, ANTIULCER AGENTS | SHIONOGI & CO., LTD. (JP) | 1982-03-09 | — | — | US | disclosed |