Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242901 | 0.97 | QPCT (0.46) | TP53ALDH1A1QPCTKDM4ETSHR | |
| SCHEMBL11240587 | 0.92 | TP53 (0.44) | TP53ALDH1A1QPCTKDM4ETSHR | |
| SCHEMBL11242340 | 0.90 | QPCT (0.47) | TP53ALDH1A1QPCTTSHRCYP19A1 | |
| SCHEMBL11241853 | 0.88 | CYP19A1 (0.44) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11230058 | 0.88 | TP53 (0.51) | TP53ALDH1A1QPCTKDM4ETSHR | |
| SCHEMBL11241810 | 0.87 | MEN1 (0.52) | TP53ALDH1A1QPCTKDM4ETSHR | |
| SCHEMBL11241916 | 0.86 | QPCT (0.48) | TP53ALDH1A1QPCTKDM4ETSHR | |
| SCHEMBL11242197 | 0.86 | QPCT (0.49) | TP53ALDH1A1QPCTKDM4ETSHR | |
| SCHEMBL11245761 | 0.85 | LMNA (0.43) | QPCTKDM4ETSHRCYP19A1 | |
| SCHEMBL11233658 | 0.85 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |