Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.81 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.78 |
| ▸ | PIM1 | P11309 | 1/20 | 0.78 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.78 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | TOP1 | P11387 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | NQO2 | P16083 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13576585 | 0.94 | PDE4D (0.76) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL30452165 | 0.91 | PDE4D (0.72) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL23202497 | 0.91 | PDE4D (0.72) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL8414778 | 0.90 | PDE4D (0.67) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL266327 | 0.88 | CHEK1 (0.80) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL10026584 | 0.88 | CHEK1 (1.00) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL7367182 | 0.88 | CHEK1 (0.80) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL21829022 | 0.87 | KMT2A (0.69) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL23202626 | 0.87 | ALDH1A1 (0.67) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL266453 | 0.86 | CHEK1 (0.76) | PDE4DCHEK1PIM1MAPK8CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342875-A | STABILIZERS FOR OLEFIN POLYMERS | CINCINNATI-MILACRON, INC. (US) | 1982-08-03 | — | — | US | disclosed |