Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.66 |
| ▸ | PIM1 | P11309 | 1/20 | 0.66 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.66 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TOP1 | P11387 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244161 | 0.90 | PDE4D (0.81) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL8417461 | 0.88 | KMT2A (0.64) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL7413404 | 0.88 | KMT2A (0.64) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL7411534 | 0.86 | POLB (0.65) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL7408481 | 0.86 | POLB (0.65) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL8414780 | 0.85 | ALDH1A1 (0.58) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL7411821 | 0.85 | ALDH1A1 (0.58) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL7407418 | 0.85 | F10 (0.79) | ALDH1A1F10POLBKMT2AMEN1 | |
| SCHEMBL13576585 | 0.84 | PDE4D (0.76) | PDE4DCHEK1PIM1MAPK8CLK4 | |
| SCHEMBL7409499 | 0.84 | MEN1 (0.61) | F10POLBKMT2ATOP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |