Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21375426 | 0.77 | — | — | |
| Ammonia Solution, Strong SCHEMBL27996117 | 0.77 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1HTTKMT2AATM | |
| SCHEMBL14376642 | 0.77 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1HTTSLC6A4KMT2A | |
| SCHEMBL1709350 | 0.76 | — | — | |
| SCHEMBL1709355 | 0.76 | — | — | |
| SCHEMBL28196279 | 0.76 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1HTTKMT2AATM | |
| SCHEMBL154109 | 0.76 | — | — | |
| SCHEMBL11279013 | 0.76 | DRD2 (0.34) | SLC6A4HRH3 | |
| SCHEMBL5675269 | 0.75 | — | — | |
| SCHEMBL11230719 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321387-A | Process for the preparation of optically active nicotine analogs | PHILIP MORRIS, INCORPORATED (US) | 1982-03-23 | — | — | US | disclosed |