⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657808 | 0.81 | — | — | |
| SCHEMBL31758285 | 0.74 | — | — | |
| SCHEMBL11244347 | 0.58 | — | — | |
| SCHEMBL28218873 | 0.58 | — | — | |
| SCHEMBL5708901 | 0.54 | TMPRSS2 (0.52) | — | |
| SCHEMBL15386143 | 0.53 | MGLL (0.35) | — | |
| SCHEMBL22031668 | 0.51 | — | — | |
| Benzoquinone SCHEMBL26923622 | 0.49 | TDP1 (0.57) | — | |
| Benzoquinone SCHEMBL28301048 | 0.47 | ALDH1A1 (0.53) | — | |
| SCHEMBL4421353 | 0.45 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004059-B1 | SYNTHESIS OF 1-(THIOCARBAMOYL)-2-IMIDAZOLIDINONE AND IMMUNOSUPPRESSIVE COMPOSITIONS CONTAINING IT | Case Western Reserve University (US) | 1982-02-17 | — | — | EP | disclosed |
| EP-0004059-A2 | Synthesis of 1-(thiocarbamoyl)-2-imidazolidinone and immunosuppressive compositions containing it | Case Western Reserve University (US) | 1979-09-19 | — | — | EP | disclosed |