Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.46 |
| ▸ | TAAR5 | O14804 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | PNLIP | P16233 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29084767 | 0.89 | MEN1 (0.43) | STK39TAAR5TAAR1MEN1KMT2A | |
| SCHEMBL9623553 | 0.85 | MEN1 (0.52) | STK39MEN1KMT2AESR1ESR2 | |
| SCHEMBL11683912 | 0.83 | MEN1 (0.56) | STK39MEN1KMT2AESR1ESR2 | |
| SCHEMBL3469104 | 0.81 | TTR (0.61) | STK39MEN1KMT2APNLIPMAPK1 | |
| SCHEMBL28345487 | 0.80 | TTR (0.59) | STK39MEN1KMT2APNLIPMAPK1 | |
| SCHEMBL29137117 | 0.79 | HDAC8 (0.37) | MEN1KMT2AHSPD1PNLIPPIK3CA | |
| SCHEMBL10664102 | 0.79 | TAAR5 (0.49) | TAAR5TAAR1MEN1KMT2AESR1 | |
| SCHEMBL10703684 | 0.79 | PDE7A (0.53) | STK39TAAR5TAAR1MEN1KMT2A | |
| SCHEMBL8683893 | 0.79 | STK39 (0.46) | STK39MEN1KMT2AESR1ESR2 | |
| SCHEMBL29084824 | 0.78 | TTR (0.52) | STK39MEN1KMT2APNLIPNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365991-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1982-12-28 | — | — | US | disclosed |