Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25957672 | 0.91 | KDM4E (0.38) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL25957699 | 0.91 | KDM4E (0.38) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL25957611 | 0.91 | KDM4E (0.38) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL16409795 | 0.81 | SMN1; SMN2 (0.43) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL14414058 | 0.80 | USP2 (0.42) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL1062380 | 0.80 | — | — | |
| SCHEMBL7705221 | 0.80 | USP2 (0.42) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL12268019 | 0.77 | — | — | |
| SCHEMBL4143916 | 0.77 | USP2 (0.63) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL4149480 | 0.77 | USP2 (0.63) | USP2TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311708-A | ADRENERGIC BLOCKING AGENTS | SYNTHELABO (FR) | 1982-01-19 | — | — | US | disclosed |
| US-4252984-A | 1-/P-/2-/CYCLOPROPYLMETHOXY/ETHYL/PHENOXY/-3-ISOPROPYLAMINO-2 -PROPANOL | SYNTHELABO (FR) | 1981-02-24 | — | — | US | disclosed |