Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 7/20 | 0.38 |
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 6/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16300471 | 0.91 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1TSHRUSP2ALOX15 | |
| SCHEMBL14414058 | 0.82 | USP2 (0.42) | ALDH1A1TSHRUSP2ALOX15KDM4E | |
| SCHEMBL125382 | 0.82 | — | — | |
| SCHEMBL1062380 | 0.82 | — | — | |
| SCHEMBL14658202 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1TSHRUSP2ALOX15 | |
| SCHEMBL7705221 | 0.82 | USP2 (0.42) | ALDH1A1TSHRUSP2ALOX15KDM4E | |
| SCHEMBL7773531 | 0.82 | CYP1A2 (0.39) | ALDH1A1TSHRUSP2ALOX15KDM4E | |
| SCHEMBL11244635 | 0.81 | USP2 (0.44) | ALDH1A1TSHRUSP2ALOX15KDM4E | |
| SCHEMBL5003314 | 0.80 | GAA (0.39) | ALDH1A1TSHRLMNAHPGDEPHX2 | |
| SCHEMBL5003310 | 0.80 | GAA (0.39) | ALDH1A1TSHRLMNAHPGDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014196328-A1 | HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF | 日本理化学工業株式会社 (JP) | 2014-12-11 | — | — | WO | disclosed |