SCHEMBL7705221

SCHEMBL7705221

CS(=O)(=O)OCC1CCC(COS(C)(=O)=O)CC1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.42
TSHR P16473 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MMP9 P14780 1/20 0.42
ALOX15 P16050 1/20 0.42
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1062380 1.00
SCHEMBL14414058 1.00 USP2 (0.42) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL18367814 0.91 KDM4E (0.36) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL6282115 0.91 KDM4E (0.36) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL121125 0.90 LMNA (0.39) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL1710717 0.90 LMNA (0.39) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL11160927 0.89 KDM4E (0.34) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL20855695 0.89 KDM4E (0.34) USP2TSHRKDM4EALDH1A1LMNA
Acetic Acid SCHEMBL2479619 0.89 SLC1A3 (0.35) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL17674869 0.89 KDM4E (0.34) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3096751-B1 12-EPI-PLEUROMUTILINS Nabriva Therapeutics GmbH (AT) 2021-01-06 EP disclosed
CN-107406379-B Non-explosive bis-sulfonyl azides 戴纳米特诺贝尔爆炸材料和系统工程有限公司 2020-10-16 CN disclosed
EP-3268352-B1 NON EXPLOSIVE BIS-SULFONYL AZIDES DYNAMIT NOBEL GMBH EXPLOSIVSTOFF UND SYSTEMTECHNIK (DE) 2020-06-10 EP disclosed
EP-3268352-B1 NON EXPLOSIVE BIS-SULFONYL AZIDES DYNAMIT NOBEL GMBH EXPLOSIVSTOFF UND SYSTEMTECHNIK (DE) 2020-06-10 EP disclosed
CN-105916499-B 12-epi-pleuromutilins 纳布里瓦治疗股份公司 2020-02-18 CN disclosed
US-10385016-B2 Non explosive bis-sulfonyl azides DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) 2019-08-20 US disclosed
US-10385016-B2 Non explosive bis-sulfonyl azides DYNAMIT NOBEL GMBH EXPLOSIVSTOFF-UND SYSTEMTECHNIK (DE) 2019-08-20 US disclosed
US-20180050988-A1 NON EXPLOSIVE BIS-SULFONYL AZIDES DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) 2018-02-22 US disclosed
US-20180050988-A1 NON EXPLOSIVE BIS-SULFONYL AZIDES DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) 2018-02-22 US disclosed
US-20180050988-A1 NON EXPLOSIVE BIS-SULFONYL AZIDES DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) 2018-02-22 US disclosed
WO-2016146597-A1 NON EXPLOSIVE BIS-SULFONYL AZIDES DYNAMIT NOBEL GMBH EXPLOSIVSTOFF- UND SYSTEMTECHNIK (DE) 2016-09-22 WO disclosed
WO-2015110481-A1 12-EPI-PLEUROMUTILINS NABRIVA THERAPEUTICS AG (AT) 2015-07-30 WO disclosed
US-6350306-B1 PAINTS AND COATINGS, ?HIGH DRY?COMPOSITIONS BASED ON FLUORINE CONTAINING POLYMERS AUSIMONT S.P.A. (IT) 2002-02-26 US disclosed
EP-0665253-B1 Coatings based on fluoropolyethers AUSIMONT SPA (IT) 2001-08-16 EP disclosed
EP-0731125-B1 Coatings based on fluoropolyethers AUSIMONT SPA (IT) 2001-07-04 EP disclosed
US-5959058-A Coatings based on fluoropolyethers AUSIMONT S.P.A. (IT) 1999-09-28 US disclosed
EP-0731125-A1 Coatings based on fluoropolyethers AUSIMONT S.p.A. (IT) 1996-09-11 EP disclosed
EP-0665253-A1 Coatings based on fluoropolyethers AUSIMONT S.p.A. (IT) 1995-08-02 EP disclosed
US-4064169-A FUNGICIDES, BACTERICIDES, ANTI-TRICHOMONAL AGENTS EISAI CO., LTD. (JA) 1977-12-20 US disclosed
US-4034010-A ANTIFUNGAL, ANTIBACTERIAL, ANTITRICHOMONAL EISAI CO., LTD. (JA) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10385016-B2 Non explosive bis-sulfonyl azides ARSA, MSRB3, NES USP2 2697/4885TSHR 3265/4885KDM4E 3517/4885
US-20180050988-A1 NON EXPLOSIVE BIS-SULFONYL AZIDES ARSA, MSRB3, NES USP2 2682/4885TSHR 3301/4885KDM4E 3481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.