Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258832 | 0.91 | PI4KB (0.59) | PI4KBALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL10643222 | 0.85 | PI4KB (0.51) | PI4KBKMT2ACYP3A4 | |
| SCHEMBL11152574 | 0.84 | SIRT2 (0.48) | ALDH1A1HPGDSIRT2SIRT1NPC1 | |
| SCHEMBL8253380 | 0.79 | SIRT2 (0.52) | ALDH1A1HPGDSIRT2SIRT1NPC1 | |
| SCHEMBL18058954 | 0.79 | MAPK14 (0.47) | PI4KBCYP3A4 | |
| SCHEMBL10643033 | 0.79 | PI4KB (0.61) | PI4KBALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL22382307 | 0.78 | KMT2A (0.63) | ALDH1A1HPGDSIRT2SIRT1NPC1 | |
| SCHEMBL18058988 | 0.78 | PI4KB (0.49) | PI4KBGAACYP3A4 | |
| SCHEMBL22382508 | 0.77 | SIRT2 (0.51) | ALDH1A1HPGDSIRT2SIRT1NPC1 | |
| SCHEMBL10640202 | 0.76 | PI4KB (0.47) | PI4KBMEN1KMT2AGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316021-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1982-02-16 | — | — | US | disclosed |
| US-4243813-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4196125-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1980-04-01 | — | — | US | disclosed |
| US-4118573-A | ANTIVIRAL AGENTS | ELI LILLY AND COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4018790-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |