Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242479 | 0.94 | MEN1 (0.46) | ATMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11229846 | 0.90 | IL2 (0.46) | ATMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11237757 | 0.87 | MEN1 (0.49) | ATMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11245158 | 0.85 | GCGR (0.54) | NPC1RAB9APKMMAPTGAA | |
| SCHEMBL11248363 | 0.83 | ATM (0.51) | ATMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10911052 | 0.82 | MEN1 (0.43) | ATMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11235860 | 0.81 | MEN1 (0.47) | ATMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11245409 | 0.81 | MEN1 (0.47) | ATMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11245400 | 0.80 | GCGR (0.60) | ATMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11243986 | 0.80 | RORC (0.64) | MEN1KMT2ANPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |