Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242479 | 0.88 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL10906957 | 0.86 | ATM (0.43) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL11244663 | 0.82 | ATM (0.49) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL11229846 | 0.79 | IL2 (0.46) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL11245409 | 0.78 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL10910904 | 0.77 | NPC1 (0.42) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL11246141 | 0.76 | ATM (0.46) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL11244669 | 0.76 | RORC (0.55) | MEN1KMT2ANPC1RAB9APKM | |
| Diflubenzuron SCHEMBL18837607 | 0.75 | RAB9A (0.59) | MEN1KMT2ANPC1RAB9APKM | |
| Diflubenzuron SCHEMBL42416 | 0.75 | RAB9A (0.59) | MEN1KMT2ANPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567295-A | Composition active against mites, whitefly and thrips, pharmaceutical composition, and new benzoylurea compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-01-28 | — | — | US | disclosed |