Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.84 |
| ▸ | MEN1 | O00255 | 1/20 | 0.84 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.84 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.84 |
| ▸ | LMNA | P02545 | 1/20 | 0.84 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.84 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.84 |
| ▸ | TSHR | P16473 | 1/20 | 0.84 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.84 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.84 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.84 |
| ▸ | ATP4A | P20648 | 1/20 | 0.84 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.84 |
| ▸ | HRH2 | P25021 | 1/20 | 0.84 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.84 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.84 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.84 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.84 |
| ▸ | ATP4B | P51164 | 1/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244714 | 1.00 | ACHE (0.84) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11250176 | 0.97 | ACHE (0.82) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11279600 | 0.97 | ACHE (0.82) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11279602 | 0.97 | ACHE (0.82) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11250179 | 0.97 | ACHE (0.82) | ACHEMEN1SLC22A1ABCB11LMNA | |
| SCHEMBL11208703 | 0.97 | ACHE (0.89) | ACHEMEN1SLC22A1ABCB11LMNA | |
| Sulfuric Acid SCHEMBL11248286 | 0.94 | ACHE (0.77) | ACHEMEN1SLC22A1ABCB11LMNA | |
| Sulfuric Acid SCHEMBL11248317 | 0.94 | ACHE (0.77) | ACHEMEN1SLC22A1ABCB11LMNA | |
| Hydrochloric Acid SCHEMBL11002727 | 0.94 | RAD52 (0.79) | ACHEMEN1SLC22A1ABCB11LMNA | |
| Hydrochloric Acid SCHEMBL11002725 | 0.94 | RAD52 (0.79) | ACHEMEN1SLC22A1ABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366164-A | HISTAMINE H2-ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1982-12-28 | — | — | US | disclosed |
| US-4317819-A | Amine derivatives | GLAXO GROUP LIMITED (GB) | 1982-03-02 | — | — | US | disclosed |
| US-4264614-A | HISTAMINE ANTAGONIST; ANTIALLERGENS; ANTISECRETORY AND ANTIINFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 1981-04-28 | — | — | US | disclosed |