Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30352517 | 0.85 | LMNA (0.56) | LMNAKMT2AMEN1POLBCYP1A2 | |
| SCHEMBL7976334 | 0.81 | KMT2A (0.64) | LMNAKMT2AMEN1POLBCYP1A2 | |
| SCHEMBL2454762 | 0.81 | KMT2A (0.59) | LMNAKMT2AMEN1POLBCYP1A2 | |
| SCHEMBL1041119 | 0.81 | CA12 (0.65) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL28565295 | 0.80 | HTT (0.60) | LMNAKMT2AMEN1POLBCYP1A2 | |
| SCHEMBL11258990 | 0.80 | CA12 (0.62) | CA12CA1CA2CA9LMNA | |
| SCHEMBL9724941 | 0.79 | MAPT (0.71) | LMNAKMT2AMEN1POLBCYP1A2 | |
| SCHEMBL28468875 | 0.79 | POLB (0.68) | LMNAKMT2AMEN1POLBCYP1A2 | |
| SCHEMBL21980929 | 0.77 | POLB (0.58) | LMNAKMT2AMEN1POLBCYP1A2 | |
| SCHEMBL27890896 | 0.77 | LMNA (0.54) | LMNAKMT2AMEN1POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310429-A | HEAT AND OXIDATION RESISTANT AMINOACETAMIDES | THE B. F. GOODRICH COMPANY (US) | 1982-01-12 | — | — | US | disclosed |
| EP-0007182-A1 | Stabilized polymers, novel stabilizers and synthesis thereof | The B.F. GOODRICH Company (US) | 1980-01-23 | — | — | EP | disclosed |