Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844038 | 0.86 | MAPT (0.66) | MAPTLMNAPOLBCYP1A2MEN1 | |
| SCHEMBL3302544 | 0.86 | POLB (0.69) | MAPTLMNAPOLBMEN1KMT2A | |
| SCHEMBL23169473 | 0.85 | LMNA (0.63) | MAPTLMNAPOLBCYP1A2MEN1 | |
| SCHEMBL9381142 | 0.85 | LMNA (0.67) | MAPTLMNAPOLBCYP1A2MEN1 | |
| SCHEMBL10576308 | 0.80 | MAPT (0.86) | MAPTLMNAPOLBCYP1A2MEN1 | |
| SCHEMBL18154533 | 0.80 | SMN1; SMN2 (0.55) | MAPTLMNAPOLBMEN1KMT2A | |
| Phenacetin SCHEMBL23280 | 0.79 | KMT2A (1.00) | MAPTLMNAPOLBCYP1A2MEN1 | |
| SCHEMBL4189931 | 0.79 | KMT2A (0.73) | MAPTLMNAPOLBCYP1A2MEN1 | |
| SCHEMBL9312707 | 0.79 | POLB (1.00) | MAPTLMNAPOLBCYP1A2MEN1 | |
| Phenacetin SCHEMBL18894356 | 0.79 | KMT2A (1.00) | MAPTLMNAPOLBCYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397274-A | Synthetic method of celiprolol drug intermediate 3-(4-ethoxyphenyl)-1,1-diethylurea | 厦门安普顿信息科技有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-105503658-A | Synthesis method of celiprolol drug intermediate 3-(4-enthoxyphenyl)-1,1-diethylurea | CHENGDU DONGDIAN AIER TECH CO LTD | 2016-04-20 | — | — | CN | claimed |
| CN-106397274-A | Synthetic method of celiprolol drug intermediate 3-(4-ethoxyphenyl)-1,1-diethylurea | 厦门安普顿信息科技有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-106397274-A | Synthetic method of celiprolol drug intermediate 3-(4-ethoxyphenyl)-1,1-diethylurea | 厦门安普顿信息科技有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-106397274-A | Synthetic method of celiprolol drug intermediate 3-(4-ethoxyphenyl)-1,1-diethylurea | 厦门安普顿信息科技有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-105503658-A | Synthesis method of celiprolol drug intermediate 3-(4-enthoxyphenyl)-1,1-diethylurea | CHENGDU DONGDIAN AIER TECH CO LTD | 2016-04-20 | — | — | CN | disclosed |
| CN-105503658-A | Synthesis method of celiprolol drug intermediate 3-(4-enthoxyphenyl)-1,1-diethylurea | CHENGDU DONGDIAN AIER TECH CO LTD | 2016-04-20 | — | — | CN | disclosed |
| CN-105503658-A | Synthesis method of celiprolol drug intermediate 3-(4-enthoxyphenyl)-1,1-diethylurea | CHENGDU DONGDIAN AIER TECH CO LTD | 2016-04-20 | — | — | CN | disclosed |
| US-5099021-A | PROCESS FOR THE PREPARATION OF PURE, UNSYMMETRICALLY DISUBSTITUTED UREAS | AGROLINZ AGRARCHEMIKALIEN GESELLSCHAFT M.B.H. (AT) | 1992-03-24 | — | — | US | disclosed |